b2b2110.2Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b2110.2Clo
• Name: Mutant line 2110.2; Bench to Bassinet Program (B2B/CVDC), mutation 2110, subline 2 Cecilia Lo
• MGI ID: MGI:5498499
• Gene: b2b2110.2Clo Location: unknown
• Alliance: b2b2110.2Clo page

Mutant 2110-002-NA has craniofacial defects, including anopthalmia, agnathia, and a bird-like snout

Show the 8 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b2110Clo. (J:175213)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b2110.2Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Cardiac phenotype: Biventricular hypertrophy
Noncardiac phenotype: Anopthalmia/micropthalmia, craniofacial defects including agnathia, micrognathia and cleft palate

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
4163	Micrognathia
4876	Cleft palate
7505	Biventricular hypertrophy

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)