Dbi^tm1Kier
Targeted Allele Detail

Summary

• Symbol: Dbi^tm1Kier
• Name: diazepam binding inhibitor; targeted mutation 1, Ann Kier
• MGI ID: MGI:5498509
• Gene: Dbi Location: Chr1:120041010-120048808 bp, - strand Genetic Position: Chr1, 52.65 cM, cytoband E2
• Alliance: Dbi^tm1Kier page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198622
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 1 and 2. QRT-PCR confirmed the absence of transcript expression in E2.5 morulas. (J:198622)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dbi Mutation: 25 strains or lines available

References

• Original: J:198622 Landrock D, et al., Acyl-CoA binding protein gene ablation induces pre-implantation embryonic lethality in mice. Lipids. 2010 Jul;45(7):567-80
• All: 1 reference(s)