Ilk^tm2Star
Targeted Allele Detail

Summary

• Symbol: Ilk^tm2Star
• Name: integrin linked kinase; targeted mutation 2, Rene St-Arnaud
• MGI ID: MGI:5499793
• Synonyms: Ilk^-
• Gene: Ilk Location: Chr7:105385799-105392132 bp, + strand Genetic Position: Chr7, 55.97 cM, cytoband E1
• Alliance: Ilk^tm2Star page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197593
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3-12 of the Ilk locus were replaced with a PGK-neo cassette. (J:197593)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ilk Mutation: 18 strains or lines available

References

• Original: J:197593 Dossa T, et al., Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption. J Cell Biochem. 2010 Jul 1;110(4):960-7
• All: 2 reference(s)