Cacna1a^smrl
Spontaneous Allele Detail

Summary

• Symbol: Cacna1a^smrl
• Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; small roller
• MGI ID: MGI:5499996
• Gene: Cacna1a Location: Chr8:85065268-85366875 bp, + strand Genetic Position: Chr8, 40.95 cM
• Alliance: Cacna1a^smrl page

Cacna1a^smrl/Cacna1a^smrl mouse (right) showing smaller body size and rolling on its side when walking compared to heterozygous control (left)

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: CXB10/HiAJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This spontaneous mutation has a an extra G inserted in the coding region of Cacna1a in the poly(G) stretch at coding nucleotides 106-110 of the cDNA (NM_001252060). (J:198844, J:222308)
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacna1a Mutation: 118 strains or lines available

References

• Original: J:198844 Harris BS, et al., Small roller: A new recessive neurological mutation that maps to Chromosome 8. MGI Direct Data Submission. 2013
• All: 2 reference(s)