Tg(Lck-Akt2*)#Test
Transgene Detail

Summary

• Symbol: Tg(Lck-Akt2*)#Test
• Name: transgene insertion, Joseph R Testa
• MGI ID: MGI:5500790
• Synonyms: Lck-MyrAkt2
• Transgene: Tg(Lck-Akt2*)#Test Location: unknown
• Alliance: Tg(Lck-Akt2*)#Test page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Akt2*)#Test expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Akt2 (MGI:104874)

• Mutation details: A cDNA for mouse Akt2 carrying a myristylation signal and using a human growth hormone polyadenylation signal was placed under the control of the Lck promoter. Six founder lines were reported (Founder lines 42, 54, 55, 62, 72, 79). (J:153923, J:154583)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Lck-Akt2*)#Test

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:153923 Timakhov RA, et al., Recurrent chromosomal rearrangements implicate oncogenes contributing to T-cell lymphomagenesis in Lck-MyrAkt2 transgenic mice. Genes Chromosomes Cancer. 2009 Sep;48(9):786-94
• All: 5 reference(s)