Stard10^tm1Saaa
Targeted Allele Detail

Summary

• Symbol: Stard10^tm1Saaa
• Name: StAR related lipid transfer domain containing 10; targeted mutation 1, Satomi Adachi-Akahane
• MGI ID: MGI:5500937
• Gene: Stard10 Location: Chr7:100966293-100995833 bp, + strand Genetic Position: Chr7, 54.55 cM
• Alliance: Stard10^tm1Saaa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198860
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 3 through 5. Western blot analysis confirmed the absence of protein expression in the liver. (J:198860)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stard10 Mutation: 21 strains or lines available

References

• Original: J:198860 Ito M, et al., Disruption of Stard10 gene alters the PPARalpha-mediated bile acid homeostasis. Biochim Biophys Acta. 2013 Feb;1831(2):459-68
• All: 1 reference(s)