Cul4b^tm1.1Pz
Targeted Allele Detail

Summary

• Symbol: Cul4b^tm1.1Pz
• Name: cullin 4B; targeted mutation 1.1, Pengbo Zhou
• MGI ID: MGI:5502166
• Synonyms: Cul4b^f
• Gene: Cul4b Location: ChrX:37622151-37665073 bp, - strand Genetic Position: ChrX, 22.81 cM, cytoband A2
• Alliance: Cul4b^tm1.1Pz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199210
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin (neo) resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neo resistance cassette. (J:199210)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cul4b Mutation: 37 strains or lines available

References

• Original: J:199210 Liu L, et al., Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis. Cell Res. 2012 Aug;22(8):1258-69
• All: 3 reference(s)