Zbtb18^tm2.1Haok
Targeted Allele Detail

Summary

• Symbol: Zbtb18^tm2.1Haok
• Name: zinc finger and BTB domain containing 18; targeted mutation 2.1, Haruo Okado
• MGI ID: MGI:5502199
• Synonyms: RP58^flox
• Gene: Zbtb18 Location: Chr1:177269917-177278330 bp, + strand Genetic Position: Chr1, 82.72 cM, cytoband H3
• Alliance: Zbtb18^tm2.1Haok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196306
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding exon. An FRT-flanked neomycin (neo) resistance cassette with a loxP site was inserted downstream of the coding exon. Flp-mediated recombination removed the neo cassette and left the coding exon floxed. (J:196306)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb18 Mutation: 26 strains or lines available

References

• Original: J:196306 Ohtaka-Maruyama C, et al., RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex. Cell Rep. 2013 Feb 21;3(2):458-71
• All: 1 reference(s)