Rpl13a^tm1.1Mazu
Targeted Allele Detail

Summary

• Symbol: Rpl13a^tm1.1Mazu
• Name: ribosomal protein L13A; targeted mutation 1.1, Barsanjit Mazumder
• MGI ID: MGI:5502322
• Gene: Rpl13a Location: Chr7:44774987-44778169 bp, - strand Genetic Position: Chr7, 29.14 cM
• Alliance: Rpl13a^tm1.1Mazu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:194920
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: One loxP site was inserted in intron 1 and a neomycin resistance cassette flanked by both FRT sites and by loxP sites was inserted following exon8. Flp recombinase was then used to remove the selection cassette from properly targed mice. Exons 2-8 were then flanked by loxP sites. (J:194920)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rpl13a Mutation: 40 strains or lines available

References

• Original: J:194920 Poddar D, et al., An extraribosomal function of ribosomal protein l13a in macrophages resolves inflammation. J Immunol. 2013 Apr 1;190(7):3600-12
• All: 3 reference(s)