Gbx1tm1.1Stwt
Targeted Allele Detail
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Symbol: |
Gbx1tm1.1Stwt |
Name: |
gastrulation brain homeobox 1; targeted mutation 1.1, Samuel T Waters |
MGI ID: |
MGI:5502431 |
Gene: |
Gbx1 Location: Chr5:24709424-24731846 bp, - strand Genetic Position: Chr5, 11.93 cM
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Alliance: |
Gbx1tm1.1Stwt page
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Locomotive defect affecting hindlimb gait in Gbx1tm1.1Stwt/Gbx1tm1.1Stwt mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:197199
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2. Whole mount in situ hybrizidation confirmed the absence of transcript expression in E9.5 embryos.
(J:197199)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gbx1 Mutation: |
19 strains or lines available
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Original: |
J:197199 Buckley DM, et al., Characterization of the Gbx1-/- mouse mutant: a requirement for Gbx1 in normal locomotion and sensorimotor circuit development. PLoS One. 2013;8(2):e56214 |
All: |
3 reference(s) |
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