Tg(Myh6-EGFP/AC3I)#Mean
Transgene Detail

Summary

• Symbol: Tg(Myh6-EGFP/AC3I)#Mean
• Name: transgene insertion, Mark Anderson
• MGI ID: MGI:5502606
• Synonyms: AC3I
• Transgene: Tg(Myh6-EGFP/AC3I)#Mean Location: unknown
• Alliance: Tg(Myh6-EGFP/AC3I)#Mean page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A sequence encoding the peptide KKALHRQEAVDCL (AC3-I) was fused to EGFP and placed under the control of the cardiac myosin heavy chain. AC3-I is an artificial peptide based on the autoinhibitory peptide of calmodulin kinase II. (J:97551)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:97551 Zhang R, et al., Calmodulin kinase II inhibition protects against structural heart disease. Nat Med. 2005 Apr;11(4):409-17
• All: 13 reference(s)