Rasd1^tm1.1Snyd
Targeted Allele Detail

Summary

• Symbol: Rasd1^tm1.1Snyd
• Name: RAS, dexamethasone-induced 1; targeted mutation 1.1, Solomon Snyder
• MGI ID: MGI:5502750
• Gene: Rasd1 Location: Chr11:59854007-59855770 bp, - strand Genetic Position: Chr11, 37.81 cM, cytoband B2
• Alliance: Rasd1^tm1.1Snyd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195135
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 1, exon 2 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:195135)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasd1 Mutation: 16 strains or lines available

References

• Original: J:195135 Chen Y, et al., Dexras1, a small GTPase, is required for glutamate-NMDA neurotoxicity. J Neurosci. 2013 Feb 20;33(8):3582-7
• All: 4 reference(s)