Etn2^tm2.1Kymm
Targeted Allele Detail

Summary

• Symbol: Etn2^tm2.1Kymm
• Name: early transposon element insertion site 2; targeted mutation 2.1, Ken-ichi Yamamura
• MGI ID: MGI:5502903
• Synonyms: kiETn
• Gene: Etn2 Location: unknown Genetic Position: Chr2, Syntenic
• Alliance: Etn2^tm2.1Kymm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:195133
• Parent Cell Line: KTPU8 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: Recombination replaced the neomycin resistance cassette in Etn2^tm1Kymm with a loxKR3, a 287 bp genomic fragment containing murine early transposon (ETn) from cosmid clone C3, FRT site, puromycin (puro) resistance cassette and lox2272 site. Flp-mediated recombination removed the puro cassette. (J:195133)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etn2 Mutation: 3 strains or lines available

References

• Original: J:195133 Semba K, et al., Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204
• All: 1 reference(s)