Tg(Ren1-cre/ERT2)1Sjs
Transgene Detail

Summary

• Symbol: Tg(Ren1-cre/ERT2)1Sjs
• Name: transgene insertion 1, Stuart J Shankland
• MGI ID: MGI:5502914
• Synonyms: Ren1cCreER
• Transgene: Tg(Ren1-cre/ERT2)1Sjs Location: unknown
• Alliance: Tg(Ren1-cre/ERT2)1Sjs page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Ren1-cre/ERT2)1Sjs expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ren1 (MGI:97898)

• Mutation details: The sequence for cre recombinase fused to mutated human estrogen receptor ligand binding domain (ERT2) was inserted into exon 1 of the renin (Ren1) gene within a 240 kb BAC (RP23-88k7). The construct was used for microinjection of fertilized zygotes. Founder and line information is not available. (J:199070)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ren1 (mouse) Summary of all recombinase alleles driven by Ren1. Comparative matrix view of recombinase activities Alliance mouse Ren1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:199070 Pippin JW, et al., Cells of Renin Lineage Are Progenitors of Podocytes and Parietal Epithelial Cells in Experimental Glomerular Disease. Am J Pathol. 2013 Aug;183(2):542-57
• All: 4 reference(s)