Ptf1a/Ptf1aostm3(CAG-Ptf1aos)Kymm
Targeted Allele Detail
|
Symbol: |
Ptf1a/Ptf1aostm3(CAG-Ptf1aos)Kymm |
Name: |
pancreas specific transcription factor, 1a; targeted mutation 3, Ken-ichi Yamamura |
MGI ID: |
MGI:5502957 |
Synonyms: |
Gm13336-Ptf1aCAG-Gm13336(1-2), Gm13336-Ptf1aGm13336(1-2) |
Gene: |
Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
|
Alliance: |
Ptf1a/Ptf1aostm3(CAG-Ptf1aos)Kymm page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:195133
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: Recombination of Ptf1a/Ptf1aostm1Kymm exchanged the floxed neomycin resistance cassette with the CAG promoter driving ubiquitous expression of the first and second exons of Ptf1aos followed by an FRT site, puromycin resistance cassette and lox2272 site. This allele was generated in ES cells containing Etn2Sd.
(J:195133)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Ptf1a Mutation: |
31 strains or lines available
|
|
Original: |
J:195133 Semba K, et al., Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice. PLoS Genet. 2013 Feb;9(2):e1003204 |
All: |
1 reference(s) |
|