Kif13a^tm1.1Noh
Targeted Allele Detail

Summary

• Symbol: Kif13a^tm1.1Noh
• Name: kinesin family member 13A; targeted mutation 1.1, Nobutaka Hirokawa
• MGI ID: MGI:5503119
• Gene: Kif13a Location: Chr13:46902563-47083343 bp, - strand Genetic Position: Chr13, 24.49 cM, cytoband B1
• Alliance: Kif13a^tm1.1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196383
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon P. A floxed lacZ and neomycin (neo) resistance cassette was inserted downstream of exon P+1. Cre-mediated recombination removed exon P, exon P+1 and the lacZ/neo cassette. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts and the brain. (J:196383)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif13a Mutation: 106 strains or lines available

References

• Original: J:196383 Zhou R, et al., A molecular motor, KIF13A, controls anxiety by transporting the serotonin type 1A receptor. Cell Rep. 2013 Feb 21;3(2):509-19
• All: 2 reference(s)