Itsn2^tm1Egan
Targeted Allele Detail

Summary

• Symbol: Itsn2^tm1Egan
• Name: intersectin 2; targeted mutation 1, Sean Egan
• MGI ID: MGI:5503193
• Gene: Itsn2 Location: Chr12:4642792-4763952 bp, + strand Genetic Position: Chr12, 2.09 cM, cytoband A1.1
• Alliance: Itsn2^tm1Egan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196062
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with an FRT-flanked neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:196062)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itsn2 Mutation: 91 strains or lines available

References

• Original: J:196062 Sengar AS, et al., Vertebrate intersectin1 is repurposed to facilitate cortical midline connectivity and higher order cognition. J Neurosci. 2013 Feb 27;33(9):4055-65
• All: 1 reference(s)