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Ifnetm1.2Pjh
Targeted Allele Detail
Summary
Symbol: Ifnetm1.2Pjh
Name: interferon epsilon; targeted mutation 1.2, Paul J Hertzog
MGI ID: MGI:5503222
Gene: Ifne  Location: Chr4:88797775-88798438 bp, - strand  Genetic Position: Chr4, 42.04 cM
Alliance: Ifnetm1.2Pjh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197569
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of the coding exon. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of the coding exon. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the coding sequence. qRT-PCR confirmed the absence of transcript expression in uterus tissue. (J:197569)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ifne Mutation:  16 strains or lines available
References
Original:  J:197569 Fung KY, et al., Interferon-epsilon protects the female reproductive tract from viral and bacterial infection. Science. 2013 Mar 1;339(6123):1088-92
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory