Ifnetm1.2Pjh
Targeted Allele Detail
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Symbol: |
Ifnetm1.2Pjh |
Name: |
interferon epsilon; targeted mutation 1.2, Paul J Hertzog |
MGI ID: |
MGI:5503222 |
Gene: |
Ifne Location: Chr4:88797775-88798438 bp, - strand Genetic Position: Chr4, 42.04 cM
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Alliance: |
Ifnetm1.2Pjh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:197569
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of the coding exon. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of the coding exon. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the coding sequence. qRT-PCR confirmed the absence of transcript expression in uterus tissue.
(J:197569)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ifne Mutation: |
16 strains or lines available
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Original: |
J:197569 Fung KY, et al., Interferon-epsilon protects the female reproductive tract from viral and bacterial infection. Science. 2013 Mar 1;339(6123):1088-92 |
All: |
3 reference(s) |
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