Del(17Fpr1-Fpr2)1Jimw
Targeted Allele Detail

Summary

• Symbol: Del(17Fpr1-Fpr2)1Jimw
• Name: deletion, Chr 17, Ji Ming Wang 1
• MGI ID: MGI:5503975
• Synonyms: Del1Jimw, Fpr1/Fpr2^tm1.1Jimw, mFPR1/2^-
• Gene: Del(17Fpr1-Fpr2)1Jimw Location: unknown Genetic Position: Chr17, Syntenic

Reduced length of colonic crypts in Fpr2^tm1.2Jimw/Fpr2^tm1.2Jimw and Del(17Fpr1-Fpr2)1Jimw/Del(17Fpr1-Fpr2)1Jimw mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197568
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(17Fpr1-Fpr2)1Jimw involves 2 genes/genome features (Fpr1, Fpr2) View all
• Mutation details: A floxed neomycin resistance cassette replaced exon 1 of Fpr1, the promoter region between the two genes and exon 1 of Fpr2. Cre-mediated recombination removed the neomycin resistance cassette. (J:197568)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(17Fpr1-Fpr2)1Jimw Mutation: 0 strains or lines available

References

• Original: J:197568 Chen K, et al., Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis. J Clin Invest. 2013 Apr 1;123(4):1694-704
• All: 1 reference(s)