Ecsit^mpc178H
Chemically induced Allele Detail

Summary

• Symbol: Ecsit^mpc178H
• Name: ECSIT signalling integrator; muta-ped-c3pde 178, Harwell
• MGI ID: MGI:5503987
• Gene: Ecsit Location: Chr9:21983542-21996734 bp, - strand Genetic Position: Chr9, 8.23 cM, cytoband A4
• Alliance: Ecsit^mpc178H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T point mutation that results in the amino acid substitution of isoleucine for asparagine at position 209 (N209I). (J:234901)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ecsit Mutation: 13 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)