Smarcc2^tm1.2Stoy
Targeted Allele Detail

Summary

• Symbol: Smarcc2^tm1.2Stoy
• Name: SWI/SNF related BAF chromatin remodeling complex subunit C2; targeted mutation 1.2, Anastassia Stoykova
• MGI ID: MGI:5504429
• Gene: Smarcc2 Location: Chr10:128295117-128326351 bp, + strand Genetic Position: Chr10, 76.59 cM
• Alliance: Smarcc2^tm1.2Stoy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197141
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 6. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neomycin resistance cassette and left exons 6 and 7 floxed. Cre-mediated recombination removed exons 6 and 7. (J:197141)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarcc2 Mutation: 56 strains or lines available

References

• Original: J:197141 Tuoc TC, et al., Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell. 2013 May 13;25(3):256-69
• All: 2 reference(s)