P4hbtm1.1Geno
Targeted Allele Detail
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Symbol: |
P4hbtm1.1Geno |
Name: |
prolyl 4-hydroxylase, beta polypeptide; targeted mutation 1.1, Genoway |
MGI ID: |
MGI:5504624 |
Synonyms: |
PDIflox |
Gene: |
P4hb Location: Chr11:120451124-120464079 bp, - strand Genetic Position: Chr11, 84.27 cM, cytoband D-E
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Alliance: |
P4hbtm1.1Geno page
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Germline Transmission: |
Earliest citation of germline transmission:
J:197556
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3'loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exons 1 and 2 floxed.
(J:197556)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any P4hb Mutation: |
32 strains or lines available
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Original: |
J:197556 Hahm E, et al., Extracellular protein disulfide isomerase regulates ligand-binding activity of alphaMbeta2 integrin and neutrophil recruitment during vascular inflammation. Blood. 2013 May 9;121(19):3789-800, S1-15 |
All: |
8 reference(s) |
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