Atp2b2^Deaf13
Chemically induced Allele Detail

Summary

• Symbol: Atp2b2^Deaf13
• Name: ATPase, Ca++ transporting, plasma membrane 2; deaf 13
• MGI ID: MGI:5505458
• Synonyms: Deaf13Mrci
• Gene: Atp2b2 Location: Chr6:113720803-114019574 bp, - strand Genetic Position: Chr6, 52.85 cM
• Alliance: Atp2b2^Deaf13 page

Abnormal cochlear hair cells in Atp2b2^Deaf11/Atp2b2^Deaf11 and Atp2b2^Deaf13/Atp2b2^Deaf13 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to A point mutation in exon 9 that results in the amino acid substitution of serine for arginine at position 561 (R561S) in the catalytic core. (J:199859)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp2b2 Mutation: 66 strains or lines available

References

• Original: J:199859 Carpinelli MR, et al., Two ENU-induced alleles of Atp2b2 cause deafness in mice. PLoS One. 2013;8(6):e67479
• All: 1 reference(s)