Sec24b^m11Bei
Chemically induced Allele Detail

Summary

• Symbol: Sec24b^m11Bei
• Name: SEC24 homolog B, COPII coat complex component; mutation 11, David R Beier
• MGI ID: MGI:5505528
• Synonyms: line 68
• Gene: Sec24b Location: Chr3:129776408-129855202 bp, - strand Genetic Position: Chr3, 59.87 cM
• Alliance: Sec24b^m11Bei page

Mutation origin

• Strain of Origin: A/J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Eight week old A/J male mice were treated weekly for three weeks with ENU. After several weeks of recovery, mice were crossed to C57BL/6 females with or without a lacZ reporter. Resulting females were backrossed to their fathers and subjected to phenotype screening. A T to A mutation in exon 2 at 129744214 Mb resulted in a Tyr84Stop codon change. (J:199782)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sec24b Mutation: 68 strains or lines available

References

• Original: J:199782 Ha S, et al., A forward genetic screen in mice identifies mutants with abnormal cortical patterning. Cereb Cortex. 2015 Jan;25(1):167-79
• All: 1 reference(s)