Tg(rx3-cre,-EGFP)MB31Zkoz
Transgene Detail

Summary

• Symbol: Tg(rx3-cre,-EGFP)MB31Zkoz
• Name: transgene insertion MB31, Zbynek Kozmik
• MGI ID: MGI:5505619
• Synonyms: MB31-Cre
• Transgene: Tg(rx3-cre,-EGFP)MB31Zkoz Location: unknown
• Alliance: Tg(rx3-cre,-EGFP)MB31Zkoz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(rx3-cre,-EGFP)MB31Zkoz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  medaka	rax

• Mutation details: The coding region of cre recombinase was cloned into a plasmid containing an IRES-EGFP sequence. The cre-IRES-EGFP cassette was fused to the medaka rx3 gene promoter to produce a transgenic construct for pronuclear injection. Nine founder animals were obtained and crossed to Rosa26 reporter mice for analysis. The line showing the least mosaic activity, MB31, was used for further characterization. (J:198990)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	rax (medaka) Summary of all recombinase alleles driven by rax. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:198990 Klimova L, et al., Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors. PLoS One. 2013;8(5):e63029
• All: 1 reference(s)