Pax7^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Pax7^{tm1.1(KOMP)Vlcg}
• Name: paired box 7; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5505636
• Gene: Pax7 Location: Chr4:139464373-139560839 bp, - strand Genetic Position: Chr4, 70.83 cM
• Alliance: Pax7^{tm1.1(KOMP)Vlcg} page
• IMPC: Pax7 gene page

Mutation origin

• Mutant Cell Lines: 14754A-D6, 14754A-G8
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 4329bp between positions 139384495-139388823 of Chromosome 4 (Genome Build37), and subsequent Cre-mediated excision removed the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax7 Mutation: 38 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 5 reference(s)