Del(2Hoxd1-Hoxd9)63Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Hoxd1-Hoxd9)63Ddu
• Name: deletion, Chr 2, Denis Duboule 63
• MGI ID: MGI:5508523
• Synonyms: Del63Ddu, HoxD^Afc
• Gene: Del(2Hoxd1-Hoxd9)63Ddu Location: Chr2:74528107-74595486 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199759
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(2Hoxd1-Hoxd9)63Ddu involves 11 genes/genome features (Hoxd9, Hoxd8, Hoxd3os1 ...) View all
• Mutation details: TAMERE recombination between Del(2Hoxd1-Hoxd13)1Ddu and Hoxd^tm13Ddu deleted Hoxd1 through Hoxd9. In situ hybridization revealed increased transcript expression of Hoxd10 in the midbrain and forebrain. (J:199759)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Hoxd1-Hoxd9)63Ddu Mutation: 0 strains or lines available

References

• Original: J:199759 Zakany J, et al., A genetic basis for altered sexual behavior in mutant female mice. Curr Biol. 2012 Sep 25;22(18):1676-80
• All: 3 reference(s)