Arpc3^tm1Ssod
Targeted Allele Detail

Summary

• Symbol: Arpc3^tm1Ssod
• Name: actin related protein 2/3 complex, subunit 3; targeted mutation 1, Scott H Soderling
• MGI ID: MGI:5509154
• Synonyms: ArpC3^f
• Gene: Arpc3 Location: Chr5:122529941-122544244 bp, + strand Genetic Position: Chr5, 62.34 cM
• Alliance: Arpc3^tm1Ssod page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196577
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was floxed. A neomycin resistance selection cassette was inserted. (J:196577)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arpc3 Mutation: 12 strains or lines available

References

• Original: J:196577 Kim IH, et al., Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities. J Neurosci. 2013 Apr 3;33(14):6081-92
• All: 9 reference(s)