Pip5k1ctm2.1Ref
Targeted Allele Detail
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Symbol: |
Pip5k1ctm2.1Ref |
Name: |
phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; targeted mutation 2.1, Reinhard Fassler |
MGI ID: |
MGI:5509203 |
Synonyms: |
PIPKIgamma- |
Gene: |
Pip5k1c Location: Chr10:81128797-81155807 bp, + strand Genetic Position: Chr10, 39.72 cM
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Alliance: |
Pip5k1ctm2.1Ref page
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Germline Transmission: |
Earliest citation of germline transmission:
J:200273
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 18. An additional loxP site was inserted downstream of exon 18. Cre-mediated recombination removed the neomycin resistance cassette and exon 18. Western blot analysis confirmed the absence of protein expression in the brain.
(J:200273)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pip5k1c Mutation: |
41 strains or lines available
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Original: |
J:200273 Legate KR, et al., Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Igamma in vivo. J Cell Sci. 2012 Dec 1;125(Pt 23):5636-46 |
All: |
1 reference(s) |
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