Pip5k1c^tm2.2Ref
Targeted Allele Detail

Summary

• Symbol: Pip5k1c^tm2.2Ref
• Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; targeted mutation 2.2, Reinhard Fassler
• MGI ID: MGI:5509205
• Synonyms: PIPKIgamma FL
• Gene: Pip5k1c Location: Chr10:81128797-81155807 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Pip5k1c^tm2.2Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200273
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 18. An additional loxP site was inserted downstream of exon 18. Flp-mediated recombination removed the neomycin resistance cassette and left exon 18 floxed. (J:200273)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pip5k1c Mutation: 41 strains or lines available

References

• Original: J:200273 Legate KR, et al., Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Igamma in vivo. J Cell Sci. 2012 Dec 1;125(Pt 23):5636-46
• All: 1 reference(s)