Mboat7^tm1Arai
Targeted Allele Detail

Summary

• Symbol: Mboat7^tm1Arai
• Name: membrane bound O-acyltransferase domain containing 7; targeted mutation 1, Hiroyoki Arai
• MGI ID: MGI:5509338
• Synonyms: Lpiat1^-
• Gene: Mboat7 Location: Chr7:3680788-3696188 bp, - strand Genetic Position: Chr7, 2.12 cM, cytoband A1
• Alliance: Mboat7^tm1Arai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200247
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 through 4. Western blot analysis confirmed the absence of protein expression in the brain, liver, kidney, testis and lung. (J:200247)

Expression

In Mice Carrying this Mutation:	17 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mboat7 Mutation: 19 strains or lines available

References

• Original: J:200247 Lee HC, et al., LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice. Mol Biol Cell. 2012 Dec;23(24):4689-700
• All: 1 reference(s)