Lig1^m1Anu
Chemically induced Allele Detail

Summary

• Symbol: Lig1^m1Anu
• Name: ligase I, DNA, ATP-dependent; mutation 1, Australian National University
• MGI ID: MGI:5510743
• Synonyms: 12BCC22a
• Gene: Lig1 Location: Chr7:13011239-13045350 bp, + strand Genetic Position: Chr7, 7.82 cM
• Alliance: Lig1^m1Anu page

Anemia in Lig1^m1Anu/Lig1^m1Anu mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6JAnu

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced an A to T substitution that results in the amino acid substitution of phenylalanine for isoleucin at position 600 (I700F). (J:199856)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lig1 Mutation: 48 strains or lines available

References

• Original: J:199856 Caruana G, et al., Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease. PLoS One. 2013;8(3):e55429
• All: 1 reference(s)