Ctdnep1^tm1Ryn
Targeted Allele Detail

Summary

• Symbol: Ctdnep1^tm1Ryn
• Name: CTD nuclear envelope phosphatase 1; targeted mutation 1, Ryuichi Nishinakamura
• MGI ID: MGI:5510826
• Synonyms: Dullard^-
• Gene: Ctdnep1 Location: Chr11:69871994-69881427 bp, + strand Genetic Position: Chr11, 42.95 cM, cytoband B4
• Alliance: Ctdnep1^tm1Ryn page

Arrested development and abnormal morphogenesis of extraembryonic tissues in Ctdnep1^tm1Ryn/Ctdnep1^tm1Ryn embryos

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199855
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neomycin resistance cassette replaced the entire coding sequence. Q-PCR confirmed the absence of transcript expression in E7.5 embryos. (J:199855)

Generation of the Ctdnep1^tm1Ryn allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctdnep1 Mutation: 20 strains or lines available

References

• Original: J:199855 Tanaka SS, et al., Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
• All: 1 reference(s)