Tbl1xr1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Tbl1xr1^tm1.1Arte
• Name: transducin (beta)-like 1X-linked receptor 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5511131
• Gene: Tbl1xr1 Location: Chr3:22130816-22270758 bp, + strand Genetic Position: Chr3, 7.58 cM
• Alliance: Tbl1xr1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198124
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 5. An F3-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exon 5 floxed. (J:198124)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbl1xr1 Mutation: 321 strains or lines available

References

• Original: J:198124 Rohm M, et al., Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue. Cell Metab. 2013 Apr 2;17(4):575-85
• All: 2 reference(s)