Tyr^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tyr^m4Btlr
• Name: tyrosinase; mutation 4, Bruce Beutler
• MGI ID: MGI:5512995
• Synonyms: Tyr^c-m4Btlr, waffle
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The waffle mutation is an A to G transition at base pair 87493221 (v38) on chromosome 7, or base pair 191 in the GenBank genomic region NC_000073 encoding Tyr. The mutation corresponds to residue 191 in the NM_011661.4 mRNA sequence in exon 1 of 5 total exons. The mutation results in a serine (S) to glycine (G) substitution at residue 44. (J:204125)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 379 strains or lines available

References

• Original: J:204125 Purrington T, et al., Direct data submission for Mutagenetix entry for waffle. MGI Direct Data Submission. 2014
• All: 1 reference(s)