Cdh23^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cdh23^m1Btlr
• Name: cadherin related 23 (otocadherin); mutation 1, Bruce Beutler
• MGI ID: MGI:5513006
• Synonyms: dee dee
• Gene: Cdh23 Location: Chr10:60138527-60532269 bp, - strand Genetic Position: Chr10, 30.11 cM
• Alliance: Cdh23^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to A transversion at base pair 60308056 (v38) on Chromosome 10, equivalent to base pair 388435 in the GenBank genomic region NC_000076 encoding Cdh23. The mutation corresponds to residue 9176 in the NM_023370.3 mRNA sequence in exon 62 of 71 total exons. The mutation also corresponds to residue 9710 in the NM_001252635 mRNA sequence in exon 61 of 70 total exons. The mutation results in a tyrosine (Y) to premature stop codon (*) substitution at amino acid residue 2923 in ENSMUSP00000101101 or residue 2921 in ENSMUSP00000101104. (J:201320)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cdh23 Mutation: 281 strains or lines available

References

• Original: J:201320 Dismang A, et al., Direct Data Submission for dee dee mutation. MGI Direct Data Submission. 2013
• All: 1 reference(s)