Cln6^{tm1b(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Cln6^{tm1b(EUCOMM)Hmgu}
• Name: ceroid-lipofuscinosis, neuronal 6; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5513756
• Gene: Cln6 Location: Chr9:62746067-62759288 bp, + strand Genetic Position: Chr9, 33.89 cM
• Alliance: Cln6^{tm1b(EUCOMM)Hmgu} page
• IMPC: Cln6 gene page

Mutation origin

• Mutant Cell Line: HEPD0727_4_B09
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre excision of MGI:4950984 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cln6 Mutation: 35 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 4 reference(s)