Dpyd^{tm1b(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dpyd^{tm1b(KOMP)Wtsi}
• Name: dihydropyrimidine dehydrogenase; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5513767
• Gene: Dpyd Location: Chr3:118355778-119226573 bp, + strand Genetic Position: Chr3, 51.96 cM
• Alliance: Dpyd^{tm1b(KOMP)Wtsi} page
• IMPC: Dpyd gene page

Mutation origin

• Mutant Cell Line: EPD0120_1_B11
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre excision of MGI:4365089 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dpyd Mutation: 65 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 5 reference(s)