Ewsr1^{tm1c(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Ewsr1^{tm1c(EUCOMM)Wtsi}
• Name: Ewing sarcoma breakpoint region 1; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:5513773
• Gene: Ewsr1 Location: Chr11:5019689-5049266 bp, - strand Genetic Position: Chr11, 3.22 cM, cytoband A1-A3
• Alliance: Ewsr1^{tm1c(EUCOMM)Wtsi} page
• IMPC: Ewsr1 gene page

Mutation origin

• Mutant Cell Line: EPD0781_4_G03
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: Flp excision of MGI:5000399 tm1a allele removes the lacZ/neo cassette leaving behind a loxP-flanked critical exon(s) (J:200814)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ewsr1 Mutation: 93 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 4 reference(s)