Idh1^{tm1b(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Idh1^{tm1b(EUCOMM)Wtsi}
• Name: isocitrate dehydrogenase 1 (NADP+), soluble; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5513791
• Gene: Idh1 Location: Chr1:65197775-65225638 bp, - strand Genetic Position: Chr1, 32.91 cM
• Alliance: Idh1^{tm1b(EUCOMM)Wtsi} page
• IMPC: Idh1 gene page

Mutation origin

• Mutant Cell Line: EPD0327_1_H02
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8A1.N3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: Cre excision of MGI:4432188 tm1a allele removes the promoter-driven neo and critical exon(s) leaving behind the lacZ reporter (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Idh1 Mutation: 44 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 5 reference(s)