Ptp4a3^tm1.2Xhan
Targeted Allele Detail

Summary

• Symbol: Ptp4a3^tm1.2Xhan
• Name: protein tyrosine phosphatase 4a3; targeted mutation 1.2, Xiao Han
• MGI ID: MGI:5514244
• Gene: Ptp4a3 Location: Chr15:73594991-73629075 bp, + strand Genetic Position: Chr15, 34.05 cM, cytoband E1
• Alliance: Ptp4a3^tm1.2Xhan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197019
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 4. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette and left exon 4 floxed. Cre-mediated recombination removed exon 4. (J:197019)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptp4a3 Mutation: 15 strains or lines available

References

• Original: J:197019 Yan H, et al., Generation of conditional knockout alleles for PRL-3. J Biomed Res. 2011 Nov;25(6):438-43
• All: 1 reference(s)