Fetub^tm1Wja
Targeted Allele Detail

Summary

• Symbol: Fetub^tm1Wja
• Name: fetuin beta; targeted mutation 1, Willi Jahnen-Dechent
• MGI ID: MGI:5514274
• Gene: Fetub Location: Chr16:22737132-22758518 bp, + strand Genetic Position: Chr16, 13.76 cM, cytoband B
• Alliance: Fetub^tm1Wja page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196435
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: (129/Sv x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in sera. (J:196435)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fetub Mutation: 39 strains or lines available

Notes

ES cell line = Knut 1

References

• Original: J:196435 Dietzel E, et al., Fetuin-B, a liver-derived plasma protein is essential for fertilization. Dev Cell. 2013 Apr 15;25(1):106-12
• All: 3 reference(s)