Gtf2h5^tm1.1Wive
Targeted Allele Detail

Summary

• Symbol: Gtf2h5^tm1.1Wive
• Name: general transcription factor IIH, polypeptide 5; targeted mutation 1.1, Wim Vermeulen
• MGI ID: MGI:5514340
• Synonyms: Ttda^-
• Gene: Gtf2h5 Location: Chr17:6130103-6135763 bp, + strand Genetic Position: Chr17, 3.7 cM
• Alliance: Gtf2h5^tm1.1Wive page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200022
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A floxed neomycin resistance cassette replaced the coding sequence in exon 3. Cre-mediated recombination removed the neomycin resistance cassette. (J:200022)

Generation of the Gtf2h5^tm1.1Wive allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gtf2h5 Mutation: 13 strains or lines available

References

• Original: J:200022 Theil AF, et al., Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality. PLoS Genet. 2013 Apr;9(4):e1003431
• All: 2 reference(s)