Mterf1b^tm1Lrsn
Targeted Allele Detail

Summary

• Symbol: Mterf1b^tm1Lrsn
• Name: mitochondrial transcription termination factor 1b; targeted mutation 1, Nils-Goran Larsson
• MGI ID: MGI:5514343
• Gene: Mterf1b Location: Chr5:4242367-4247651 bp, + strand Genetic Position: Chr5, 2.34 cM
• Alliance: Mterf1b^tm1Lrsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The second exon was replaced with a hygromycin resistance cassette. ES cells containing this allele were used to generate Mterf1a^tm1.1Lrsn. (J:198969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mterf1b Mutation: 14 strains or lines available

References

• Original: J:198969 Terzioglu M, et al., MTERF1 binds mtDNA to prevent transcriptional interference at the light-strand promoter but is dispensable for rRNA gene transcription regulation. Cell Metab. 2013 Apr 2;17(4):618-26
• All: 1 reference(s)