Gfra1^{tm1(cre/ERT2)Sjn}
Targeted Allele Detail

Summary

• Symbol: Gfra1^{tm1(cre/ERT2)Sjn}
• Name: glial cell line derived neurotrophic factor family receptor alpha 1; targeted mutation 1, Sanjay Jain
• MGI ID: MGI:5514386
• Gene: Gfra1 Location: Chr19:58224036-58444341 bp, - strand Genetic Position: Chr19, 54.18 cM, cytoband D2-D3
• Alliance: Gfra1^{tm1(cre/ERT2)Sjn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199323
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Gfra1^{tm1(cre/ERT2)Sjn} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gfra1 (MGI:1100842)

• Mutation details: A cre/ERT2 cassette was inserted into the second exon of Gpra1 by homologous recombination in ES cells. (J:199323)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gfra1 (mouse) Summary of all recombinase alleles driven by Gfra1. Alliance mouse Gfra1 gene page

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gfra1 Mutation: 33 strains or lines available

References

• Original: J:199323 Keefe Davis T, et al., Stage specific requirement of Gfralpha1 in the ureteric epithelium during kidney development. Mech Dev. 2013 Sep-Oct;130(9-10):506-18
• All: 2 reference(s)