Rif1^MommeD18
Chemically induced Allele Detail

Summary

• Symbol: Rif1^MommeD18
• Name: replication timing regulatory factor 1; modifier of murine metastable epialleles, D18
• MGI ID: MGI:5515365
• Gene: Rif1 Location: Chr2:51962844-52012395 bp, + strand Genetic Position: Chr2, 29.98 cM
• Alliance: Rif1^MommeD18 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: A C-to-T single point mutation in exon 29 is predicted to result in a Q1669 to a stop codon in the encoded protein. The encoded protein was not detected on Western blot of embryonic tissue, suggesting that this allele is null. (J:201508)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rif1 Mutation: 172 strains or lines available

References

• Original: J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96
• All: 1 reference(s)