M1185b
Chemically induced Allele Detail

Summary

• Symbol: M1185b
• Name: mutant 1185b
• MGI ID: MGI:5515459
• Synonyms: line 1185
• Gene: M1185b Location: unknown Genetic Position: Chr13, Syntenic
• Alliance: M1185b page

Mutation origin

• Strain of Origin: mixed

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: This mutation was identified in an ENU mutagenesis screen focused on the Del(13)36H deletion interval, which encompasses 12.66 Mb, or approximately 20%, of mouse Chromosome (Chr) 13 including bands A3.1 through A4. The deleted segment shares synteny with regions of human 6p25 and 6p22 associated with 6p deletion syndromes and 6p associated disorders. (J:101156)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any M1185b Mutation: 2 strains or lines available

Notes

This allele was induced by ENU treatment of a male mouse homozygous for Foxq1^sa on a mixed genetic background (mostly 101 and C3H, but derived from a linkage testing stock also homozygous for Wnt3a^vt (origin: C57BR) and Bloc1s5^mu (origin: t-allele stock)).

References

• Original: J:101156 Bogani D, et al., Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12477-82
• All: 1 reference(s)