Hmx1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Hmx1^tm1.1Arte
• Name: H6 homeobox 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5515732
• Synonyms: Hmx1^fl
• Gene: Hmx1 Location: Chr5:35546452-35557074 bp, + strand Genetic Position: Chr5, 18.14 cM
• Alliance: Hmx1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198834
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 2 floxed. (J:198834)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmx1 Mutation: 10 strains or lines available

References

• Original: J:198834 Furlan A, et al., The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification. EMBO J. 2013 May 29;32(11):1613-25
• All: 1 reference(s)