4933427D14Rik^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: 4933427D14Rik^{tm1.1(KOMP)Vlcg}
• Name: RIKEN cDNA 4933427D14 gene; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5515778
• Synonyms: 4933427D14Rik^-, Mnr^-
• Gene: 4933427D14Rik Location: Chr11:72044755-72098308 bp, - strand Genetic Position: Chr11, Syntenic
• Alliance: 4933427D14Rik^{tm1.1(KOMP)Vlcg} page
• IMPC: 4933427D14Rik gene page

4933427D14Rik^{tm1.1(KOMP)Vlcg}/4933427D14Rik^{tm1.1(KOMP)Vlcg} mice exhibit embryonic lethality embryos recovered at E7.5 but not at E9.5. Embryos exhibit abnormal embryo turning and growth retardation at E8.5.

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: 18550A-G4
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 32716bp between positions 71983288-72016003 of Chromosome 11 (Genome Build37), and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	55 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any 4933427D14Rik Mutation: 42 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 7 reference(s)