Brap^tm1.1Yfng
Targeted Allele Detail

Summary

• Symbol: Brap^tm1.1Yfng
• Name: BRCA1 associated protein; targeted mutation 1.1, Yuanyi Feng
• MGI ID: MGI:5515812
• Gene: Brap Location: Chr5:121798626-121825312 bp, + strand Genetic Position: Chr5, 61.9 cM, cytoband F
• Alliance: Brap^tm1.1Yfng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197131
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP/Frt flanked neomycin selection cassette was inserted in intron 1 and a third loxP site was placed in intron 3. Subsequent cre expression then excised the selection cassette and both exons 2 and 3. (J:197131)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brap Mutation: 30 strains or lines available

References

• Original: J:197131 Lanctot AA, et al., Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
• All: 4 reference(s)